We ask what it takes to make this transformation permanent. In other words:
Is the result after the transition morphologically and epigenetically changed? (A)
Or is the transition product morphologically, epigenetically and genetically altered? (B) - We tend to favor this option.
If future investigators of any gDNA of genes could include two kbp upstream of the first exon, all introns, and .5 kbp downstream of the last exon, that would be a great help in searching for TATA-boxes in these regions.
March 2020 rolfy